In postmenopausal osteoporosis, oestrogen deficiency causes high-turnover bone loss with an increase in the number and depth of remodelling sites. Areas with large amounts of trabecular bone are most affected; therefore, wrist and vertebral fractures tend to be more common. Age-related osteoporosis occurs in men and women over the age of 75 and is due to decrease in calcium absorption, vitamin D levels, osteoblast function and life span, and sex hormone production. Cortical and trabecular bone are both affected, leading to increase in all types of fractures, particularly hip fractures.
The standard diagnostic test for Osteoporosis is Bone Mineral Density by DEXA scan.
Treatment of osteoporosis depends upon the severity assessed on DEXA scan. This includes, Calcium & Vitamin D supplements, Bisphosphonates, Calcitonin supplements, and Teri-paratide injections.Leave a reply →